meleda disease การใช้

• "' Meleda disease "'( MDM ) or " "'mal de Meleda "'", also called "'Mljet disease "', "'keratosis palmoplantaris "'and "'transgradiens of siemens "', ( also known as " Acral keratoderma, " and " Palmoplantar keratoderma of the Norrbotten type " ) is an extremely rare autosomal recessive congenital skin disorder in which dry, thick patches of skin develop on the soles of the hands and feet, a condition known as palmoplantar hyperkeratosis.